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Latent Membrane Protein 1 and the B Lymphocyte-A Complex Relationship

1 Jan 2014

Abstract excerpt

The Epstein Barr Virus (EBV)-encoded latent membrane protein 1 (LMP1) exerts numerous impacts on the functions of B lymphocytes, the cell type in which EBV establishes long-term latent infections. LMP1 expression has been implicated in making important contributions to a variety of human malignancies, as well as to autoimmune diseases. EBV also infects other types of immune cells, as well as nasopharyngeal...

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PMID: 24941072
DOI: 10.1615/critrevimmunol.2014010041

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