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Article

Relationship between the debrisoquine hydroxylase polymorphism and cancer susceptibility.

Carcinogenesis - 1 Jun 1992

Wolf C R, Smith C A, Gough A C, Moss J E, Vallis K A, Howard G, Carey F J, Mills K, McNee W, Carmichael J

Abstract excerpt

There have been a series of reports on the association of a genetic polymorphism at the cytochrome P450 CYP2D6 gene locus with cancer susceptibility. Many of these reports have remained contradictory either because of small numbers of patients studied or because of the limitations and controversy surrounding the pharmacokinetic assay used to identify affected individuals (poor metabolizers; PMs). We have recently...

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PMID: 1600608
DOI: 10.1093/carcin/13.6.1035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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