Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chromosomal loci influencing the susceptibility to the parkinsonian neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 10 Sept 2003

Sedelis Marco, Hofele Katja, Schwarting Rainer K W, Huston Joseph P, Belknap John K

Abstract excerpt

Parkinson's disease (PD) is a neurodegenerative disorder characterized by the dysfunction of the nigrostriatal dopaminergic pathway. Although its etiology is not yet fully understood, an interaction of genetic predisposition and environmental factors is frequently discussed. The neurotoxin 1-meth...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bayes Theorem
Share to Chromosomes
Share to Dopamine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Monte Carlo Method

Share to Neostriatum

Share to Neurotoxins

Share to Parkinsonian Disorders

Share to Survival Rate

Source

Open in PubMed Open full text

Identifiers

PMID: 12967986
PMCID: PMC6740699

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12967986-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chromosomal loci influencing the susceptibility to the parkinsonian neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.PMID 12967986Read ↗

Identification of a single QTL, Mptp1, for susceptibility to MPTP-induced substantia nigra pars compacta neuron loss in mice.Semantic proximity Read ↗

Systems analysis of genetic variation in MPTP neurotoxicity in mice.Semantic proximity Read ↗

MPTP susceptibility in the mouse: behavioral, neurochemical, and histological analysis of gender and strain differences.Semantic proximity Read ↗

Genetic dissection of strain dependent paraquat-induced neurodegeneration in the substantia nigra pars compacta.Semantic proximity Read ↗

Epidemiologic approaches to the study of Parkinson's disease etiology.Semantic proximity Read ↗

Behavioral phenotyping of the MPTP mouse model of Parkinson's disease.Semantic proximity Read ↗

Genetic and environmental risk factors in Parkinson's disease.Semantic proximity Read ↗

The interplay between environmental and genetic factors in Parkinson's disease susceptibility: the evidence for pesticides.Semantic proximity Read ↗

MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity.Semantic proximity Read ↗

Gene-environment interaction models to unmask susceptibility mechanisms in Parkinson's disease.Semantic proximity Read ↗

Genetic-based, differential susceptibility to paraquat neurotoxicity in mice.Semantic proximity Read ↗

Strain- and age-dependent features of the nigro-striatal circuit in three common laboratory mouse strains, C57BL/6J, A/J, and DBA/2J - <i>Implications for Parkinson’s disease modeling</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.