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Article

Behavioral phenotyping of the MPTP mouse model of Parkinson's disease.

Behavioural brain research - 1 Nov 2001

Sedelis M, Schwarting R K, Huston J P

Abstract excerpt

In mice, the systemical or intracranial application of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) can lead to severe damage to the nigrostriatal dopaminergic system. This can result in a variety of symptoms concerning motor control resembling those in human Parkinson's dis...

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Source

Identifiers

PMID: 11682102
DOI: 10.1016/s0166-4328(01)00309-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11682102-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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