Article

Strain- and age-dependent features of the nigro-striatal circuit in three common laboratory mouse strains, C57BL/6J, A/J, and DBA/2J - <i>Implications for Parkinson’s disease modeling</i>

2020-12-01

Abstract excerpt

Mouse models have been instrumental in understanding genetic determinants of aging and its crucial role in neurodegenerative diseases. However, few studies have analyzed the evolution of the mouse brain over time at baseline. Furthermore, mouse brain studies are commonly conducted on the C57BL/6 strain, limiting the analysis to a specific genetic background. In Parkinson’s disease, the gradual demise of nigral dop...

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Literature Corpus work: 7003404f-2f95-5f50-89b0-8c4dd2df7f7e
DOI: 10.1101/2020.11.30.404293

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Strain- and age-dependent features of the nigro-striatal circuit in three common laboratory mouse strains, C57BL/6J, A/J, and DBA/2J - <i>Implications for Parkinson’s disease modeling</i>DOI 10.1101/2020.11.30.404293Read

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