Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A modified mutagenic PCR-RFLP method for K-ras codon 12 and 13 mutations detection in NSCLC patients.

Molecular and cellular probes - 1 Oct 2001

Hatzaki A, Razi E, Anagnostopoulou K, Iliadis K, Kodaxis A, Papaioannou D, Labropoulos S, Vasilaki M, Kosmidis P, Saetta A, Mihalatos M, Nasioulas G

Abstract excerpt

Evidence from many investigators has shown that mutations in the first exon of K- ras gene occur at elevated frequencies in lung, pancreatic and colon carcinoma and seem to be of prognostic importance. The aim of this study was to develop an effective method for the detection of K- ras mutations in codons 12 and 13 in non-small-cell lung cancer (NSCLC) patients in order to investigate correlation with clinical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to Codon

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, ras

Share to Greece

Share to Lung Neoplasms

Share to Neoplasm Staging

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 11735295
DOI: 10.1006/mcpr.2001.0367

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A modified mutagenic PCR-RFLP method for K-ras codon 12 and 13 mutations detection in NSCLC patients.PMID 11735295Read ↗

Modified mismatch polymerase chain reaction-restriction fragment length polymorphism detected mutations in codon 12 and 13 of exon 2 of K-ras gene in colorectal cancer patients and its association with liver metastases: Data from a South Asian country.Semantic proximity Read ↗

[K-ras gene mutation in colorectal cancer and its clinicopathologic significance].Semantic proximity Read ↗

Correlation between K-ras gene mutation and prognosis of patients with nonsmall cell lung carcinoma.Semantic proximity Read ↗

Frequency and spectrum of mutations at codons 12 and 13 of the c-K-ras gene in human tumors.Semantic proximity Read ↗

ras gene mutations in non-small cell lung cancers are associated with shortened survival irrespective of treatment intent.Semantic proximity Read ↗

Low frequency of p53 and k-ras codon 12 mutations in non-small cell lung carcinoma (NSCLC) tumors and surgical margins.Semantic proximity Read ↗

Automated real-time PCR to determine K-ras codon 12 mutations in non-small cell lung cancer: comparison with immunohistochemistry and clinico-pathological features.Semantic proximity Read ↗

k-RAS mutation and resistance to epidermal growth factor receptor-tyrosine kinase inhibitor treatment in patients with nonsmall cell lung cancer.Semantic proximity Read ↗

Detection of codon 61 point mutations of the K-ras gene in lung and colorectal cancers by enriched PCR.Semantic proximity Read ↗

Implications and prognostic value of K-ras mutation for early-stage lung cancer in women.Semantic proximity Read ↗

Frequency and spectrum of K-RAS codons 12 and 13 mutations in colorectal adenocarcinomas from Taiwan.Semantic proximity Read ↗

Detection of codon 12 mutation in the K-ras oncogene in pancreatic tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.