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Article

Prognostic and predictive value of K-RAS mutations in non-small cell lung cancer.

Drugs - 19 Jun 2012

Califano Raffaele, Landi Lorenza, Cappuzzo Federico

Abstract excerpt

Non-small cell lung cancer (NSCLC) is a heterogeneous disease, caused by the presence of different clinically relevant molecular subtypes. Genetic mutations are emerging as potential biomarkers of response and treatment selection in patients with NSCLC. Over the past few years, activating mutations of epidermal growth factor receptor (EGFR) have been recognized as the most important predictor of response to EGFR...

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Identifiers

PMID: 22712795
DOI: 10.2165/1163012-S0-000000000-00000

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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