Article
Variants of the CD40 ligand gene are not associated with increased susceptibility to tuberculosis in West Africa.
Immunogenetics - 1 Oct 2003
Campbell Sarah J, Sabeti Pardis, Fielding Katherine, Sillah Jackson, Bah Boubacar, Gustafson Per, Manneh Kebba, Lisse Ida, Sirugo Giorgio, Bellamy Richard, Bennett Steve, Aaby Peter, McAdam Keith P W J, Bah-Sow Oumou, Lienhardt Christian, Hill Adrian V S
Abstract excerpt
Evidence for linkage between tuberculosis and human chromosomal region Xq26 has previously been described. The costimulatory molecule CD40 ligand, encoded by TNFSF5 and located at Xq26.3, is a promising positional candidate. Interactions between CD40 ligand and CD40 are involved in the developmen...
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