Article
Polymorphism of X-linked CD40 ligand gene associated with pulmonary tuberculosis in the Han Chinese population.
Genes and immunity - 1 Sept 2015
Hu C-Y, Zhang X-A, Meyer C G, Thye T, Liu W, Cao W-C
Abstract excerpt
Among those developing tuberculosis (TB) after exposure to Mycobacterium tuberculosis, approximately 70% are males. Host genetic variation, particularly immune-related genes on the X chromosome, may contribute to sex-specific differences in TB incidences. To study whether X-linked gene variation is associated with sex-specific presentation of pulmonary TB (pTB), three single-nucleotide polymorphisms (SNPs) of the...
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