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Article

Mapping of a novel susceptibility locus suggests a role for MC3R and CTSZ in human tuberculosis.

American journal of respiratory and critical care medicine - 15 Jul 2008

Cooke Graham S, Campbell Sarah J, Bennett Steve, Lienhardt Christian, McAdam Keith P W J, Sirugo Giorgio, Sow Oumou, Gustafson Per, Mwangulu Frank, van Helden Paul, Fine Paul, Hoal Eileen G, Hill Adrian V S

Abstract excerpt

RATIONALE: Tuberculosis remains a major cause of morbidity and mortality in the developing world. A better understanding of the mechanisms of disease protection could allow novel strategies to disease management and control. OBJECTIVES: To identify human genomic loci with evidence of linkage to tuberculosis susceptibility and, within these loci, to identify individual genes influencing tuberculosis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18420963
DOI: 10.1164/rccm.200710-1554OC
PMCID: PMC2643210

Genes

CTSZ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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