Article
Host genetic susceptibility to human tuberculosis.
Novartis Foundation symposium - 1 Jan 1998
Bellamy R J, Hill A V
Abstract excerpt
Convincing evidence exists that host genes influence the outcome of infection in human tuberculosis. We are employing two complementary strategies to find the genes involved: a linkage-based, comprehensive genome screen and an association-based candidate gene study. In a genome screen of 282 markers on 92 affected sib pairs we have found evidence of co-segregation of disease with five markers, but further studies...
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