Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2.

doi:10.1038/ng.639

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Article

Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2.

Nature genetics - 1 Sept 2010

Thye Thorsten, Vannberg Fredrik O, Wong Sunny H, Owusu-Dabo Ellis, Osei Ivy, Gyapong John, Sirugo Giorgio, Sisay-Joof Fatou, Enimil Anthony, Chinbuah Margaret A, Floyd Sian, Warndorff David K, Sichali Lifted, Malema Simon, Crampin Amelia C, Ngwira Bagrey, Teo Yik Y, Small Kerrin, Rockett Kirk, Kwiatkowski Dominic, Fine Paul E, Hill Philip C, Newport Melanie, Lienhardt Christian, Adegbola Richard A, Corrah Tumani, Ziegler Andreas, Morris Andrew P, Meyer Christian G, Horstmann Rolf D, Hill Adrian V S

Abstract excerpt

We combined two tuberculosis genome-wide association studies from Ghana and The Gambia with subsequent replication in a combined 11,425 individuals. rs4331426, located in a gene-poor region on chromosome 18q11.2, was associated with disease (combined P = 6.8 x 10(-9), odds ratio = 1.19, 95% CI =...

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Identifiers

PMID: 20694014
DOI: 10.1038/ng.639
PMCID: PMC4975513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20694014-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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