Article
Fine mapping of a putative tuberculosis-susceptibility locus on chromosome 15q11-13 in African families.
Human molecular genetics - 1 Jul 2002
Cervino Alessandra C L, Lakiss Said, Sow Oumou, Bellamy Richard, Beyers Nulda, Hoal-van Helden Eileen, van Helden Paul, McAdam Keith P W J, Hill Adrian V S
Abstract excerpt
Host genetics plays an important role in individual susceptibility and resistance to infectious diseases, but no genes have yet been identified using genome-wide screens. Twin studies have indicated that tuberculosis susceptibility has a significant host genetic component, and several genes appear to be involved. Recently, a genome-wide linkage analysis of 136 African families identified chromosome 15q11-13 as a...
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