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Article

Rapid genotyping of tumor necrosis factor alpha with fluorogenic hybridization probes on the LightCycler.

Clinical and experimental medicine - 1 Dec 2008

Hayashi Naoko, Imamura Yu, Hiyoshi Yukiharu, Takamori Hiroshi, Beppu Toru, Hirota Masahiko, Baba Hideo

Abstract excerpt

Genotyping of tumor necrosis factor alpha (TNF-alpha) has become an important procedure in the selection of high-risk population of septic shock and prevention from death due to septic shock. We present a single-tube method for TNF-alpha genotyping that performed on the LightCycler by melting curve analysis with allele-specific fluorescent probe. A fragment covering the polymorphic site is amplified in the...

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PMID: 18815866
DOI: 10.1007/s10238-008-0009-x

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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