Article
Acoustic startle and prepulse inhibition in 40 inbred strains of mice.
Behavioral neuroscience - 1 Aug 2003
Willott James F, Tanner Lisa, O'Steen Jennifer, Johnson Kenneth R, Bogue Molly A, Gagnon Leona
Abstract excerpt
A high-throughput phenotype screening protocol was used to measure the acoustic startle response (ASR) and prepulse inhibition (PPI) in mice. ASRs were evoked by noise bursts; prepulses for PPI were 70 dB sound pressure level tones of 4, 12, and 20 kHz. Forty inbred strains of mice were tested (in most cases using 10 males and 10 females of each strain). The data on both the ASR and PPI had high internal and...
Topics
- Acoustic Stimulation
- Animals
- Female
- Male
- Mice
- Mice, Inbred Strains
- Phenotype
- Reference Values
- Reflex, Startle