Independent genetic loci for sensorimotor gating and attentional performance in BXD recombinant inbred strains.

doi:10.1111/j.1601-183X.2011.00754.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Independent genetic loci for sensorimotor gating and attentional performance in BXD recombinant inbred strains.

Genes, brain, and behavior - 1 Mar 2012

Loos M, Staal J, Pattij T, Smit A B, Spijker S

Abstract excerpt

A startle reflex in response to an intense acoustic stimulus is inhibited when a barely detectable pulse precedes the startle stimulus by 30-500 ms. It has been theorized that this phenomenon, named prepulse inhibition (PPI) of a startle response, is an automatic early-stage gating process contributing to the ability to focus attention. Deficits in PPI may therefore contribute to deficits in attentional...

Topics

Acoustic Stimulation
Animals
Attention
Behavior, Animal
Decision Making
Genetic Loci
Genotype
Mice
Mice, Inbred Strains
Quantitative Trait Loci
Reaction Time
Reflex
Reflex, Startle
Sensory Gating
Species Specificity

Source

Open in PubMed

Identifiers

PMID: 22098762
DOI: 10.1111/j.1601-183X.2011.00754.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics