Genetics, haloperidol-induced catalepsy and haloperidol-induced changes in acoustic startle and prepulse inhibition.

doi:10.1007/s002130050434

Back to search

Article

Genetics, haloperidol-induced catalepsy and haloperidol-induced changes in acoustic startle and prepulse inhibition.

Psychopharmacology - 1 Nov 1997

McCaughran J, Mahjubi E, Decena E, Hitzemann R

Abstract excerpt

The acoustic startle response (ASR), prepulse inhibition (PPI) of the ASR and the effects of haloperidol on the ASR and PPI were examined in C57BL/6J (B6) and DBA/2 (D2) inbred mouse strains and their F1 and F2 progeny. The startle stimulus was a 60-ms, 110-dB, 10-kHz tone; the prepulse stimuli w...

Topics

Acoustic Stimulation
Animals
Antipsychotic Agents
Catalepsy
Genotype
Haloperidol
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Reflex, Startle

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.