Article
Assessment of locomotor activity, acoustic and tactile startle, and prepulse inhibition of startle in inbred mouse strains and F1 hybrids: implications of genetic background for single gene and quantitative trait loci analyses.
Neuroscience - 1 Oct 1997
Logue S F, Owen E H, Rasmussen D L, Wehner J M
Abstract excerpt
As the use of transgenic and null mutation techniques in the development of animal models of disorders increases, the importance of selecting the appropriate genetic background also increases. The genetic background of the mouse strains used as models for various disorders is critical because of...
Topics
- Acoustic Stimulation
- Analysis of Variance
- Animals
- Crosses, Genetic
- Female
- Male
- Maze Learning
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Mice, Inbred Strains
- Models, Genetic
- Motor Activity
- Phenotype
- Physical Stimulation
- Reflex, Startle
- Species Specificity
- Touch