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Article

Cutting edge: expansion of the KIR locus by unequal crossing over.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2003

Martin Maureen P, Bashirova Arman, Traherne James, Trowsdale John, Carrington Mary

Abstract excerpt

The killer Ig-like receptor (KIR) genes have high sequence similarity and are organized in a head-to-tail fashion. These properties may enhance misalignment of homologous chromosomes during synapsis preceding meiotic recombination, resulting in unequal crossing over. We have identified an extended KIR haplotype that contains a novel hybrid gene and two copies of each of two previously described KIR genes. A...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12928362
DOI: 10.4049/jimmunol.171.5.2192

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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