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Article

Conserved KIR allele-level haplotypes are altered by microvariation in individuals with European ancestry.

Genes and immunity - 1 Jan 2012

Hou L, Chen M, Ng J, Hurley C K

Abstract excerpt

NK cell immunoglobulin-like receptor (KIR) haplotype-specific DNA fragments were sequenced to identify centromeric and telomeric allele-level haplotype structures and their frequencies from 76 unrelated individuals with European ancestry. Analysis was simplified by redefining the 5' boundary of the centromeric KIR gene cluster to include only exons 7-9 of KIR3DL3. Three consensus allele-level haplotypes were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21796155
DOI: 10.1038/gene.2011.52
PMCID: PMC3536055

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