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Article

Abnormal mucosal extracellular matrix deposition is associated with increased TGF-beta receptor-expressing mesenchymal cells in a mouse model of colitis.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Sept 2003

Whiting Christine V, Tarlton John F, Bailey Michael, Morgan Clare L, Bland Paul W

Abstract excerpt

Transforming growth factor-beta (TGF-beta) depresses mucosal inflammation and upregulates extracellular matrix (ECM) deposition. We analyzed TGF-beta receptors RI and RII as well as ECM components using the CD4(+) T-cell-transplanted SCID mouse model of colitis. The principal change in colitis wa...

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Source

Identifiers

PMID: 12923243
DOI: 10.1177/002215540305100908

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12923243-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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