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Article

Fibrogenic signals in patients with radiation enteritis are associated with increased connective tissue growth factor expression.

International journal of radiation oncology, biology, physics - 1 Jun 2003

Vozenin-Brotons Marie Catherine, Milliat Fabien, Sabourin Jean Christophe, de Gouville Anne Charlotte, François Agnès, Lasser Philipe, Morice Philipe, Haie-Meder Christine, Lusinchi Antoine, Antoun Sami, Bourhis Jean, Mathé Denis, Girinsky Theo, Aigueperse Jocelyne

Abstract excerpt

PURPOSE: To investigate the expression of a new fibrogenic cytokine the connective tissue growth factor (CTGF) in intestinal radiation fibrosis and to characterize the mesenchymal cell subtypes involved in CTGF synthesis and collagen deposition. METHODS AND MATERIALS: Sixteen patients with radiation enteritis that occurred after radiotherapy for pelvic malignancies and 6 with histologically normal bowel entered...

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PMID: 12738334
DOI: 10.1016/s0360-3016(02)04601-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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