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Article

Cooperative binding of Sox10 to DNA: requirements and consequences.

Nucleic acids research - 15 Dec 2002

Schlierf Beate, Ludwig Andreas, Klenovsek Karin, Wegner Michael

Abstract excerpt

The high-mobility-group (HMG) domain containing transcription factor Sox10 is an important regulator of various processes including the development of neural crest cells and glial cells. Target gene promoters contain multiple Sox10-binding sites, which either support monomeric or cooperative, dimeric binding. The latter is unusual for Sox proteins and might contribute to functional specificity of Sox10. We find...

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Identifiers

PMID: 12490719
DOI: 10.1093/nar/gkf690
PMCID: PMC140074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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