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Article

Sox2 and Pou2f1 interact to control lens and olfactory placode development.

Developmental biology - 15 Mar 2007

Donner Amy L, Episkopou Vasso, Maas Richard L

Abstract excerpt

Sox2, which encodes an SRY-like HMG box transcription factor, is critical for vertebrate development. Sox2 mediates its transcriptional effects through the formation of complexes with specific co-factors, many of which are unknown. In this report, we identify Oct-1, encoded by the Pou2f1 gene, as a co-factor for Sox2 in the context of mouse lens and nasal placode induction. Oct-1, Sox2, and Pax6 are co-expressed...

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Topics

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Share to Anophthalmos
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 17140559
DOI: 10.1016/j.ydbio.2006.10.047
PMCID: PMC3276313

Genes

SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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