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Article

Different applications of polymerases with and without proofreading activity in single-nucleotide polymorphism analysis.

Laboratory investigation; a journal of technical methods and pathology - 1 Aug 2003

Zhang Jia, Li Kai, Liao Duanfang, Pardinas Jose R, Chen Linling, Zhang Xu

Abstract excerpt

With the completion of the human genome project, single-nucleotide polymorphisms (SNPs) have become the focus of intense study in biomedical research. Polymerase-mediated primer extension has been employed in a variety of SNP assays. However, these SNP assays using polymerase without proofreading...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12920243
DOI: 10.1097/01.lab.0000081589.91390.df

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12920243-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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