Article
New performance from an old member: SNP assay and de novo sequencing mediated by exo+ DNA polymerases.
Journal of biochemistry and molecular biology - 31 May 2004
Zhang Jia, Li Kai
Abstract excerpt
DNA polymerases without the 3' exonuclease function (exo(-) pol) have been widely used in sequencing and SNP genotyping. As a major player that expedited the coming of the postgenomic era, exo(-) polymerases worked remarkably well in the Human Genome Sequencing Project. However, it has become a c...
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