Article
Only truncated, not complete cytochrome p450 2D6 RNA transcript and no detectable enzyme activity are expressed in human lymphocytes.
Drug metabolism and disposition: the biological fate of chemicals - 1 Sept 2003
McConnachie Lisa A, Phillips Brian, Bajpai Manoj, Shen Danny D, Ho Rodney J Y
Abstract excerpt
Genotyping of the highly polymorphic cytochrome p450 2D6 (CYP2D6) permits a gross classification of individual phenotype (viz. ultra-rapid, extensive, and poor metabolizers). It does not, however, provide a precise prediction of CYP2D6 activity, particularly in an individual possessing at least o...
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