Article
Genetic susceptibility to carrageenan-induced innate inflammatory response in inbred strains of rats.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 2003
Joe B, Garrett M R, Dene H, Remmers E F, Meng H
Abstract excerpt
Rat models are useful for the genetic dissection of the biology of innate immunity. Inbred rat strains were evaluated for carrageenan-induced innate inflammatory responses. Results indicated that the genetic control of innate immune responses is polygenic and influenced by gender, and may not necessarily be consistent with the genetics of experimental arthritis. The newly identified susceptible strains, in order...
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