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Article

The origin of the autoimmune disease-resistant LER rat: an outcross between the buffalo and autoimmune disease-prone Lewis inbred rat strains.

Journal of neuroimmunology - 1 May 1993

Goldmuntz E A, Wilder R L, Goldfarb Y, Cash J M, Zha H, Crofford L J, Mathern P, Hansen C T, Remmers E F

Abstract excerpt

The Lewis (LEW) rat strain is highly susceptible to a large number of experimentally induced inflammatory and autoimmune diseases. The Lewis resistant (LER) rat strain, which reportedly arose as a spontaneous mutation in a closed colony of LEW rats, is resistant to many of these disorders. The mechanism of resistance is not yet clear. We report the analysis of 19 simple dinucleotide repeat polymorphisms in 13 rat...

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PMID: 8505411
DOI: 10.1016/0165-5728(93)90046-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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