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Article

Identification of a novel inflammation-protective locus in the Fischer rat.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 1999

Listwak S, Barrientos R M, Koike G, Ghosh S, Gomez M, Misiewicz B, Sternberg E M

Abstract excerpt

Inbred LEW/N rats are relatively susceptible, while histocompatible inbred F344/N rats are relatively resistant to development of a wide variety of inflammatory diseases in response to a range of pro-inflammatory stimuli. In a LEW/N vs. F344/N F2 intercross, we identified a quantitative trait locus (QTL) on Chr 10 that protects in a dominant fashion against the exudate volume component of innate inflammation in...

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PMID: 10087293
DOI: 10.1007/s003359901002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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