Article
The determinants of susceptibility/resistance to adjuvant arthritis in rats.
Arthritis research & therapy - 1 Jan 2009
Kim Eugene Y, Moudgil Kamal D
Abstract excerpt
Adjuvant arthritis (AA) serves as an excellent model for human rheumatoid arthritis. AA is readily inducible in certain rat strains, but not in others. Susceptibility/resistance to AA is determined by multiple factors. Among the genetic factors, both MHC and non-MHC genes contribute to arthritis susceptibility, and specific quantitative trait loci show association with the severity of the disease. Differential...
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