Candidate gene region 15q26 and genetic susceptibility to coeliac disease in Finnish families.

doi:10.1080/003655201300051153

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Article

Candidate gene region 15q26 and genetic susceptibility to coeliac disease in Finnish families.

Scandinavian journal of gastroenterology - 1 Apr 2001

Susi M, Holopainen P, Mustalahti K, Mäki M, Partanen J

Abstract excerpt

BACKGROUND: Studies in the Irish and British populations have indicated that chromosome region 15q26 could include a novel non-HLA-linked locus conferring genetic susceptibility to coeliac disease. The locus is of particular interest, since a type I diabetes risk locus, IDDM3, maps to the same position. It was tested whether this locus shows evidence for genetic linkage to coeliac disease in Finland. METHODS:...

Topics

Celiac Disease
Chromosomes, Human, Pair 15
Female
Finland
Genetic Linkage
Genetic Predisposition to Disease
Genetics, Population
HLA-DQ Antigens
Humans
Incidence
Male
Microsatellite Repeats
Population Surveillance
Probability
Sensitivity and Specificity

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PMID: 11336161
DOI: 10.1080/003655201300051153

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