Article
Genetic association of coeliac disease susceptibility to polymorphisms in the ICOS gene on chromosome 2q33.
Genes and immunity - 1 Mar 2004
Haimila K, Smedberg T, Mustalahti K, Mäki M, Partanen J, Holopainen P
Abstract excerpt
An interesting candidate gene region for coeliac disease (CD), a common multifactorial disease, is a segment on 2q33-37 harbouring the genes for the CD28, cytotoxic T-lymphocyte-associated antigen-4 (CTLA4), inducible costimulator (ICOS), and programmed death-1 (PD-1), all receptors that regulate...
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