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Article

Epitope map for a growth hormone receptor agonist monoclonal antibody, MAb 263.

Molecular endocrinology (Baltimore, Md.) - 1 Nov 2003

Wan Yu, Zheng Yuan Zhi, Harris Jonathan M, Brown Richard, Waters Michael J

Abstract excerpt

Monoclonal antibody (MAb) 263 is a widely used monoclonal antibody that recognizes the extracellular domain (ECD) of the GH receptor. It has been shown to act as a GH agonist both in vitro and in vivo, and we report here that it must be divalent to exert its effect on the full-length receptor. To...

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Source

Identifiers

PMID: 12907759
DOI: 10.1210/me.2003-0162

Genes

ECD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12907759-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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