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Article

Mutations of APC, K-ras, and p53 are associated with specific chromosomal aberrations in colorectal adenocarcinomas.

Cancer research - 1 Aug 2003

Leslie Amy, Pratt Norman R, Gillespie Karen, Sales Mark, Kernohan Neil M, Smith Gillian, Wolf C Roland, Carey Francis A, Steele Robert J C

Abstract excerpt

It is widely accepted that both large-scale chromosomal abnormalities and mutation of specific genes, such as APC, K-ras, and/or p53, occur in the majority of colorectal adenocarcinomas. Whether or not a relationship exists between these different forms of genetic abnormalities was previously unk...

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PMID: 12907646

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12907646-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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