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Article

Prognostic value of p53 overexpression and c-Ki-ras gene mutations in colorectal cancer.

Gastroenterology - 1 Jan 1993

Bell S M, Scott N, Cross D, Sagar P, Lewis F A, Blair G E, Taylor G R, Dixon M F, Quirke P

Abstract excerpt

BACKGROUND: Mutations in Ki-ras codon 12 and the p53 gene are common abnormalities in colorectal cancer. The occurrence of p53 overexpression and/or Ki-ras codon 12 mutations were analyzed in 100 colorectal adenomas to determine if they were related to patient survival. METHODS: p53 overexpression was identified by immunohistochemistry, and Ki-ras codon 12 mutations were detected using the polymerase chain...

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Source

Identifiers

PMID: 8419262
DOI: 10.1016/0016-5085(93)90835-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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