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Article

Prognostic value of p53 overexpression and c-Ki-ras gene mutations in colorectal cancer.

Gastroenterology - 1 Jan 1993

Bell S M, Scott N, Cross D, Sagar P, Lewis F A, Blair G E, Taylor G R, Dixon M F, Quirke P

Abstract excerpt

BACKGROUND: Mutations in Ki-ras codon 12 and the p53 gene are common abnormalities in colorectal cancer. The occurrence of p53 overexpression and/or Ki-ras codon 12 mutations were analyzed in 100 colorectal adenomas to determine if they were related to patient survival. METHODS: p53 overexpressio...

Topics

Adenocarcinoma
Antibodies, Monoclonal
Codon
Colorectal Neoplasms
Gene Expression
Genes, p53
Genes, ras
Humans
Immunohistochemistry
Mutation
Ploidies
Prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Survival Analysis

Tumor Suppressor Protein p53

Source

Identifiers

PMID: 8419262
DOI: 10.1016/0016-5085(93)90835-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8419262-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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