Article
Nucleotide excision repair proteins may be involved in the fixation of glyoxal-induced mutagenesis in Escherichia coli.
Biochemical and biophysical research communications - 20 Jul 1998
Murata-Kamiya N, Kamiya H, Kaji H, Kasai H
Abstract excerpt
To investigate the influence of nucleotide excision repair (NER) on glyoxal-induced mutations, we treated wild-type and NER-deficient (uvrC) Escherichia coli strains with glyoxal, and analyzed mutations in the chromosomal lacI gene. In both strains, the cell death and the mutation frequency incre...
Topics
- Bacterial Proteins
- Base Composition
- Base Sequence
- DNA Repair
- Escherichia coli
- Escherichia coli Proteins
- Glyoxal
- Lac Repressors
- Molecular Sequence Data
- Mutagenesis
- Mutation
- Repressor Proteins
- Sequence Analysis, DNA