Article
Detecting interacting genetic loci with effects on quantitative traits where the nature and order of the interaction are unknown.
Genetic epidemiology - 1 May 2010
Davies Joanna L, Hein Jotun, Holmes Chris C
Abstract excerpt
Standard techniques for single marker quantitative trait mapping perform poorly in detecting complex interacting genetic influences. When a genetic marker interacts with other genetic markers and/or environmental factors to influence a quantitative trait, a sample of individuals will show different effects according to their exposure to other interacting factors. This paper presents a Bayesian mixture model,...
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