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Article

Polyamines in a genetic animal model of paroxysmal dyskinesia.

Brain research - 15 Aug 2003

Richter Angelika, Morrison Lesley D

Abstract excerpt

Previous studies suggested that glutamatergic overactivity contributes to the manifestation of dystonia in the dt(sz) mutant hamster, a model of idiopathic paroxysmal dyskinesia in which dystonic episodes occur in response to mild stress. Therefore, the role of polyamines, known as positive modulators of NMDA receptors, was examined in the present study. The levels of polyamines (putrescine, spermidine, spermine)...

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Source

Identifiers

PMID: 12885438
DOI: 10.1016/s0006-8993(03)03022-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polyamines in a genetic animal model of paroxysmal dyskinesia.PMID 12885438Read ↗

The NMDA receptor NR2B subtype selective antagonist Ro 25-6981 aggravates paroxysmal dyskinesia in the dt(sz) mutant.Semantic proximity Read ↗

Extracellular amino acid levels in the striatum of the dt(sz) mutant, a model of paroxysmal dystonia.Semantic proximity Read ↗

Effects of intrastriatal injections of glutamate receptor antagonists on the severity of paroxysmal dystonia in the dtsz mutant.Semantic proximity Read ↗

Role of striatal NMDA receptor subunits in a model of paroxysmal dystonia.Semantic proximity Read ↗

Increased levels of kynurenic acid in brains of genetically dystonic hamsters.Semantic proximity Read ↗

Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia.Semantic proximity Read ↗

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