Article
Altered expression of preproenkephalin and prodynorphin mRNA in a genetic model of paroxysmal dystonia.
Brain research - 23 Jul 2004
Nobrega J N, Parkes J H, Wong P, Raymond R, Richter A
Abstract excerpt
The dtsz mutant hamster represents a model of primary paroxysmal dystonia, in which dystonic episodes occur in response to stress. Previous examinations demonstrated striatal dysfunctions in dtsz hamsters. In the present study, in situ hybridization was used to examine preproenkephalin and prodynorphin expression as potential indices of imbalances between the striatopallidal and striatonigral pathways. Brain...
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