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Article

Role of striatal NMDA receptor subunits in a model of paroxysmal dystonia.

Experimental neurology - 1 Nov 2014

Avchalumov Yosef, Sander Svenja E, Richter Franziska, Porath Katrin, Hamann Melanie, Bode Christoph, Kirschstein Timo, Köhling Rüdiger, Richter Angelika

Abstract excerpt

Dystonia is a movement disorder in which abnormal plasticity in the basal ganglia has been hypothesized to play a critical role. In a model of paroxysmal dystonia, the dt(sz) mutant hamster, previous studies indicated striatal dysfunctions, including an increased long-term potentiation (LTP). Beneficial effects were exerted by subunit-unspecific antagonists at NMDA receptors, which blocked LTP. NR2B subtype...

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Identifiers

PMID: 25139804
DOI: 10.1016/j.expneurol.2014.08.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of striatal NMDA receptor subunits in a model of paroxysmal dystonia.PMID 25139804Read ↗

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