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Article

Msx1 controls inductive signaling in mammalian tooth morphogenesis.

Development (Cambridge, England) - 1 Oct 1996

Chen Y, Bei M, Woo I, Satokata I, Maas R

Abstract excerpt

Members of the Msx homeobox family are thought to play important roles in inductive tissue interactions during vertebrate organogenesis, but their precise developmental function has been unclear. Mice deficient for Msx1 exhibit defects in craniofacial development and a failure of tooth morphogenesis, with an arrest in molar tooth development at the E13.5 bud stage. Because of its potential for experimental...

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Source

Identifiers

PMID: 8898217
DOI: 10.1242/dev.122.10.3035

Genes

BMP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Msx1 controls inductive signaling in mammalian tooth morphogenesis.PMID 8898217Read ↗

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Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development.Semantic proximity Read ↗

Msx homeobox gene family and craniofacial development.Semantic proximity Read ↗

MSX1 Drives Tooth Morphogenesis Through Controlling Wnt Signaling ActivitySemantic proximity Read ↗

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BMP signaling orchestrates a transcriptional network to control the fate of mesenchymal stem cells in miceSemantic proximity Read ↗

Postnatal Msx1 expression pattern in craniofacial, axial, and appendicular skeleton of transgenic mice from the first week until the second year.Semantic proximity Read ↗

Msx1 and Dlx5 act independently in development of craniofacial skeleton, but converge on the regulation of Bmp signaling in palate formation.Semantic proximity Read ↗

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