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Article

Light does not degrade the constitutively expressed BMAL1 protein in the mouse suprachiasmatic nucleus.

The European journal of neuroscience - 1 Jul 2003

von Gall Charlotte, Noton Elizabeth, Lee Choogon, Weaver David R

Abstract excerpt

Biological rhythms in mammals are driven by a central circadian clock located in the suprachiasmatic nucleus (SCN). At the molecular level the biological clock is based on the rhythmic expression of clock genes. Two basic helix-loop-helix (bHLH)/PAS-containing transcription factors, CLOCK and BMAL1 (MOP3), provide the basic drive to the system by activating transcription of negative regulators through E box...

Topics

ARNTL Transcription Factors
Actins
Animals
Antibody Specificity
Basic Helix-Loop-Helix Transcription Factors
CLOCK Proteins
Circadian Rhythm
Genes, fos
Genotype
Image Processing, Computer-Assisted

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunoblotting

Immunohistochemistry

Light

Male

Mice

Mice, Inbred C3H

Perfusion

Precipitin Tests

Source

Identifiers

PMID: 12859345
DOI: 10.1046/j.1460-9568.2003.02735.x

Genes

BMAL1
CLOCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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Light does not degrade the constitutively expressed BMAL1 protein in the mouse suprachiasmatic nucleus.PMID 12859345Read ↗

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