Article
Phenotype matters: identification of light-responsive cells in the mouse suprachiasmatic nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 7 Jan 2004
Karatsoreos Ilia N, Yan Lily, LeSauter Joseph, Silver Rae
Abstract excerpt
The suprachiasmatic nucleus (SCN) of the hypothalamus is the neural locus of the circadian clock. To explore the organization of the SCN, two strains of transgenic mice, each bearing a jellyfish green fluorescent protein (GFP) reporter, were used. In one, GFP was driven by the promoter region of the mouse Period1 gene (mPer1) (Per1::GFP mouse), whereas in the other, GFP was inserted in the promoter region of...
Topics
- Animals
- Calbindins
- Cell Cycle Proteins
- Circadian Rhythm
- Gastrin-Releasing Peptide
- Gene Expression Regulation
- Green Fluorescent Proteins
- Light
- Luminescent Proteins
- Mice
- Mice, Transgenic
- Nuclear Proteins
- Period Circadian Proteins