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Early Inhibition of Retinoic Acid Signaling Rapidly Generates Cardiomyocytes Expressing Ventricular Markers from Human Induced Pluripotent Stem Cells

2019-11-26

Abstract excerpt

<h4>SUMMARY</h4> Current protocols for the differentiation of cardiomyocytes from human induced pluripotent stem cells (iPSCs) generally require prolonged time in culture and result in heterogeneous cellular populations. We present a method for the generation of beating cardiomyocytes expressing specific ventricular markers after just 14 days. Addition of the pan-retinoic acid receptor inverse agonist BMS 493 to...

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Literature Corpus work
5b2bcf86-a1a1-5604-885f-206157b80b86
DOI
10.1101/856575
Open publication

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