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Sbk2, a Newly Discovered Atrium-Enriched Regulator of Sarcomere Integrity

19 May 2022

Abstract excerpt

BACKGROUND: Heart development relies on tight spatiotemporal control of cardiac gene expression. Genes involved in this intricate process have been identified using animals and pluripotent stem cell-based models of cardio(myo)genesis. Recently, the repertoire of cardiomyocyte differentiation models has been expanded with iAM-1, a monoclonal line of conditionally immortalized neonatal rat atrial myocytes (NRAMs),...

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PMID: 35587025
DOI: 10.1161/circresaha.121.319300

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