Article
Gene Expression Profiling of H9c2 Myoblast Differentiation towards a Cardiac-Like Phenotype.
PloS one - 1 Jan 2015
Branco Ana F, Pereira Susana P, Gonzalez Susana, Gusev Oleg, Rizvanov Albert A, Oliveira Paulo J
Abstract excerpt
H9c2 myoblasts are a cell model used as an alternative for cardiomyocytes. H9c2 cells have the ability to differentiate towards a cardiac phenotype when the media serum is reduced in the presence of all-trans-retinoic acid (RA), creating multinucleated cells with low proliferative capacity. In the present study, we performed for the first time a transcriptional analysis of the H9c2 cell line in two...
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