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Article

Incision at hypoxanthine residues in DNA by a mammalian homologue of the Escherichia coli antimutator enzyme endonuclease V.

Nucleic acids research - 15 Jul 2003

Moe Ane, Ringvoll Jeanette, Nordstrand Line M, Eide Lars, Bjørås Magnar, Seeberg Erling, Rognes Torbjørn, Klungland Arne

Abstract excerpt

Deamination of DNA bases can occur spontaneously, generating highly mutagenic lesions such as uracil and hypoxanthine. In Escherichia coli two enzymes initiate repair at hypoxanthine residues in DNA. The alkylbase DNA glycosylase, AlkA, initiates repair by removal of the damaged base, whereas end...

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Identifiers

PMID: 12853604
DOI: 10.1093/nar/gkg472
PMCID: PMC167633

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12853604-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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