Rodent UV-sensitive mutant cell lines in complementation groups 6-10 have normal general excision repair activity.

doi:10.1093/nar/25.5.1015

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Article

Rodent UV-sensitive mutant cell lines in complementation groups 6-10 have normal general excision repair activity.

Nucleic acids research - 1 Mar 1997

Reardon J T, Thompson L H, Sancar A

Abstract excerpt

Mammalian nucleotide excision repair is the primary enzymatic pathway for removing bulky lesions from DNA. The repair reaction involves three main steps: (i) dual incisions on both sides of the lesion; (ii) excision of the damaged base in an oligonucleotide 24-31 nt in length; (iii) filling in of...

Topics

Animals
CHO Cells
Cell Line
Cricetinae
DNA
DNA Damage
DNA Repair
Genetic Complementation Test
HeLa Cells
Humans
Mutation
Rodentia
Ultraviolet Rays

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