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Article

Mouse methyltransferase for repair of O6-methylguanine and O4-methylthymine in DNA.

Carcinogenesis - 1 Jul 1995

Kawate H, Ihara K, Kohda K, Sakumi K, Sekiguchi M

Abstract excerpt

cDNA for mouse O6-methylguanine-DNA methyltransferase was expressed in methyltransferase-deficient Escherichia coli mutant cells, and the overproduced mouse enzyme was purified to a homogeneous state. Using this purified product, polyclonal antibodies were prepared and used to estimate amounts of...

Topics

3T3 Cells
Animals
Base Sequence
DNA Repair
DNA, Complementary
Guanine
HeLa Cells
Humans
Immunoblotting
Intracellular Fluid
Methylnitronitrosoguanidine
Methyltransferases
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred BALB C

Molecular Sequence Data

Mutation

O(6)-Methylguanine-DNA Methyltransferase

Substrate Specificity

Source

Identifiers

PMID: 7614694
DOI: 10.1093/carcin/16.7.1595

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7614694-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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